Amoxicillin
Aminopenicillin Antibiotic
Amoxicillin is a first-line antibiotic during pregnancy for susceptible bacterial infections (UTIs, upper respiratory tract infections, dental infections). Decades of clinical use show zero teratogenic risk.
Amoxicillin is considered one of the safest antibiotics in pregnancy. Untreated maternal bacterial infections pose far greater risks (preterm labor, pyelonephritis) than amoxicillin therapy.
Safe. No increased risk of structural birth defects.
Safe for UTIs, respiratory, or ENT infections.
Safe.
Achieves therapeutic concentration in fetal circulation.
Extensive human pregnancy registries show no association with congenital malformations.
Mild diarrhea or nausea.
Prescribe standard adult dosage for indicated bacterial infections.
Finish the full antibiotic course prescribed by your doctor.
- Monitor for allergic skin rash
- Repeat urine culture after UTI treatment
- Renal clearance of amoxicillin increases during the 2nd and 3rd trimesters.
Amoxicillin is very safe to take during pregnancy. Treating bacterial infections promptly prevents complications like premature labor.
Yes, amoxicillin has been used safely by millions of pregnant women across all trimesters.
Decades of global clinical safety data and guidelines.
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1
U.S. Food and Drug Administration (FDA) PLLR — FDA Pregnancy and Lactation Labeling Rule & Approved Prescribing Information Database Last updated: Official FDA Standard
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2
FDA Center for Drug Evaluation and Research (CDER) — FDA MedWatch & Black Box Warning Database Last updated: Official FDA Standard
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3
ACOG Practice Bulletins & Guidelines — American College of Obstetricians and Gynecologists Clinical Recommendations Last updated: 2025 Clinical Edition
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4
Briggs Drugs in Pregnancy and Lactation — Reference Guide to Fetal and Neonatal Risk (12th Edition) Last updated: 2025 Clinical Edition