PEER-REVIEWED CLINICAL MNEMONICS

Medical Memory Palace

Textbook-verified clinical mnemonics, diagnostic frameworks, and pharmacology cheat sheets aggregated from First Aid USMLE, Harrison's 21e, BNF, and Robbins Pathology.

53+ Clinical Mnemonics First Aid & Harrison's 21e 11 Specialties 100% Textbook Verified
53+ Mnemonics
11 Specialties
100% Verified
Clinical & Educational Disclaimer: Mnemonics and clinical frameworks are designed for rapid recall, medical board examination review (USMLE, IFOM, PLAB), and structured clinical cognition. Always correlate with primary clinical guidelines, definitive diagnostics, and comprehensive patient evaluation.
Showing all 53 mnemonics
Endocrinology Beginner
STONES, BONES, GROANS, PSYCHIATRIC OVERTONES

Hypercalcemia Symptoms & Signs

STONES BONES GROANS PSYCHIATRIC OVERTONES

Classic medical rhyme describing systemic manifestations of severe hypercalcemia (serum Ca2+ > 12 mg/dL).

Stones Renal Calculi & Nephrocalcinosis
Bones Bone Pain & Osteitis Fibrosa Cystica
Groans Abdominal Groans
Cardiology Beginner
MONA BATS

Acute Coronary Syndrome Initial Management

MONA BATS

Classic protocol for immediate emergency department stabilization and secondary prevention of Acute Myocardial Infarction.

M Morphine
O Oxygen
N Nitroglycerin
Pharmacology Intermediate
SICKFACES.COM

Cytochrome P450 Enzyme Inhibitors

S I C K F A C E S . +

Classic mnemonic for major CYP450 enzyme inhibitors that elevate substrate drug levels and cause toxicities.

S Sodium Valproate
I Isoniazid (INH)
C Cimetidine
Nephrology Intermediate
C BIG K DROP

Hyperkalemia Management Protocol: C BIG K DROP

C BIG K DROP

Step-by-step emergency medical stabilization and total body elimination of severe hyperkalemia (K+ > 6.5 mEq/L or with ECG changes).

C Calcium Gluconate / Calcium Chloride
B Beta-2 Agonists (Albuterol / Salbutamol)
I Insulin (Regular) + Glucose
Emergency Medicine Intermediate
5 H's & 5 T's

Reversible Causes of Cardiac Arrest: 5 H's & 5 T's

5 H's & 5 T's

The ACLS checklist of reversible physiological insults causing pulseless electrical activity (PEA) and asystole.

H1 Hypovolemia
H2 Hypoxia
H3 Hydrogen Ion (Acidosis)
Nephrology Intermediate
INFLAMMATION vs PODOCYTE PODIUM

Nephritic vs Nephrotic Syndrome Cheat Sheet

INFLAMMATION vs PODOCYTE PODIUM

Core clinical and urinalysis distinctions between glomerular inflammation (Nephritic) and glomerular charge/barrier breakdown (Nephrotic).

Nephritic CAPS: Casts, Azotemia, Pressure (HTN), Sed...
Nephrotic PEAL: Proteinuria (>3.5g), Edema, Albumin...
Thrombosis Hypercoagulability in Nephrotic
Nephrology Intermediate
BUN:Cr & FENa CHEAT SHEET

Prerenal vs Intrinsic AKI Differentiation

BUN:Cr & FENa CHEAT SHEET

Diagnostic markers differentiating prerenal hypoperfusion from intrinsic acute tubular necrosis (ATN).

BUN:Cr > 20:1 Prerenal Azotemia
BUN:Cr < 15:1 Intrinsic Renal (ATN)
FENa < 1% Prerenal (Avid Na+ Reabsorption)
Hematology Intermediate
TAILS

Microcytic Hypochromic Anemias

T A I L S

Differential diagnosis for microcytic anemias defined by Mean Corpuscular Volume (MCV) < 80 fL.

T Thalassemia (Alpha or Beta)
A Anemia of Chronic Disease (Inflammation)
I Iron Deficiency Anemia (IDA)
Cardiology Intermediate
CHA2DS2-VASc

Atrial Fibrillation Stroke Risk: CHA2DS2-VASc

C H A 2 D S 2 - V A +

Validated clinical prediction rule estimating 1-year ischemic thromboembolic stroke risk in patients with non-valvular atrial fibrillation.

C Congestive Heart Failure (+1)
H Hypertension (+1)
A2 Age >= 75 years (+2)
Infectious Disease Intermediate
ToRCHHeS

Congenital Intrauterine Infections

T o R C H H e S

Group of vertically transmitted perinatal infections causing microcephaly, chorioretinitis, sensorineural hearing loss, and hepatosplenomegaly.

T Toxoplasma gondii
R Rubella Virus
C Cytomegalovirus (CMV)
Endocrinology Advanced
MEN 1, 2A, 2B (3-P, 2-P-1-M, 1-P-2-M)

Multiple Endocrine Neoplasia (MEN) Syndromes

MEN 1 2A 2B 3-P 2-P-1-M 1-P-2-M

Autosomal dominant neoplastic syndromes grouped by organs beginning with the letters P and M.

MEN 1 3 P's (Pituitary, Parathyroid, Pancreas)
MEN 2A 2 P's, 1 M (Parathyroid, Pheo, Medullary)
MEN 2B 1 P, 2 M's (Pheo, Medullary, Mucosal/Marfa...
Pharmacology Intermediate
TERATO

Teratogenic Drugs High-Yield List

T E R A T O

The highest-yield universally tested medications that cause severe fetal structural malformations when taken during pregnancy.

T Thalidomide & Tetracyclines
E Epilepsy Drugs (Valproate, Phenytoin, Carb...
R Retinoids (Isotretinoin)
Infectious Disease Intermediate
FROM JANE

Infective Endocarditis: Duke Criteria

FROM JANE

Clinical signs and minor criteria under the modified Duke criteria for diagnosing infective endocarditis.

F Fever (> 38°C / 100.4°F)
R Roth Spots
O Osler Nodes
Psychiatry Beginner
DIG FAST

Bipolar Manic Episode Criteria

DIG FAST

DSM-5 diagnostic criteria for Mania requiring abnormally elevated, expansive, or irritable mood for at least 1 week.

D Distractibility
I Impulsivity / Indiscretion
G Grandiosity
Gastroenterology Intermediate
CHARCOT & REYNOLDS

Acute Cholangitis: Charcot Triad & Reynolds Pentad

CHARCOT & REYNOLDS

Clinical indicators of acute bacterial ascending cholangitis, differentiating uncomplicated cholangitis from septic biliary emergency.

F Fever & Chills
J Jaundice
R RUQ Abdominal Pain
Neurology Beginner
BE-FAST

Acute Stroke Warning Signs: BE-FAST

B E - F A S T

Modern emergency public and clinical screening protocol for identifying acute ischemic and hemorrhagic strokes.

B Balance (Sudden Loss of Balance / Coordina...
E Eyes (Sudden Vision Loss / Diplopia)
F Face (Facial Drooping / Asymmetry)
Neurology Beginner
TRAP

Parkinson's Disease Cardinal Motor Signs

T R A P

The four cardinal motor features of idiopathic Parkinson's disease resulting from substantia nigra dopaminergic degeneration.

T Tremor (Pill-Rolling at Rest)
R Rigidity (Cogwheel & Lead-Pipe)
A Akinesia / Bradykinesia
Psychiatry Beginner
SIGECAPS

Major Depressive Disorder Diagnostic Criteria

S I G E C A P S

DSM-5 diagnostic criteria for a Major Depressive Episode requiring >= 5 symptoms for at least 2 consecutive weeks.

S Sleep Disturbance
I Interest Loss (Anhedonia)
G Guilt / Worthlessness
Psychiatry Advanced
FEVER

Neuroleptic Malignant Syndrome Features

F E V E R

Life-threatening idiosyncratic reaction to dopamine D2-receptor antagonist antipsychotics.

F Fever (Hyperthermia)
E Encephalopathy
V Vitals Unstable (Autonomic Instability)
Nephrology Intermediate
MUDPILES

High Anion Gap Metabolic Acidosis

M U D P I L E S

The gold-standard clinical mnemonic for etiologies of elevated serum anion gap metabolic acidosis (AG > 12 mEq/L).

M Methanol
U Uremia (Advanced Renal Failure)
D Diabetic Ketoacidosis (DKA)
Pharmacology Beginner
BLIND AS A BAT, MAD AS A HATTER

Anticholinergic Toxidrome Signs

BLIND AS A BAT MAD AS A HATTER

Rhyme summarizing competitive muscarinic receptor blockade seen with diphenhydramine, tricyclic antidepressants, and belladonna alkaloids.

Blind Blind as a bat (Mydriasis & Cycloplegia)
Mad Mad as a hatter (Delirium & Hallucinations...
Red Red as a beet (Flushed Skin)
Hematology Intermediate
EX-PRESIDENT vs IN-SIDE

Coagulation Pathways & Antidotes: Warfarin vs Heparin

EX-PRESIDENT vs IN-SIDE

Essential clinical cheat sheet distinguishing Warfarin (Extrinsic / PT) from Heparin (Intrinsic / aPTT).

Warfarin WEPT: Warfarin Extrinsic Pathway PT/INR
Heparin Heparin = INtrinsic Pathway = aPTT
Teratogen Warfarin = Teratogen; Heparin = Safe in Pr...
Pharmacology Beginner
SLUDGE / DUMBELS

Cholinergic Toxidrome Symptoms

SLUDGE DUMBELS

Classic toxidrome caused by organophosphate pesticides or nerve agents that irreversibly inhibit acetylcholinesterase.

D Defecation / Diarrhea
U Urination
M Miosis & Muscle Fasciculation
Hematology Beginner
CRAB

Multiple Myeloma Clinical Features

C R A B

Classic diagnostic tetrad of end-organ damage caused by monoclonal malignant plasma cell proliferation.

C Calcium (Hypercalcemia)
R Renal Insufficiency (Cr > 2 mg/dL)
A Anemia (Normocytic Normochromic)
Gastroenterology Intermediate
I GET SMASHED

Acute Pancreatitis Etiologies

I GET SMASHED

The classic, highest-yield mnemonic for recalling causes of acute pancreatitis, with gallstones and alcohol accounting for ~70% of presentations.

I Idiopathic
G Gallstones
E Ethanol (Alcohol)
Pharmacology Intermediate
ABCDEFG

Drugs Causing QT Prolongation

A B C D E F G

High-yield medication classes that block hERG potassium channels (IKr), prolonging ventricular repolarization and risking Torsades de Pointes.

A Antiarrhythmics (Class IA & III)
B antiBiotics (Macrolides & Fluoroquinolones...
C anti-C (Citalopram & Chloroquine)
Emergency Medicine Beginner
GCS: E4 V5 M6

Glasgow Coma Scale: Breakdown & Scoring

GCS E4 V5 M6

Objective clinical tool used to assess consciousness and coma depth following head injury or medical trauma.

Eyes (1-4 4: Spontaneous, 3: To voice, 2: To pain, 1...
Verbal (1-5 5: Oriented, 4: Confused, 3: Words, 2: Sou...
Motor (1-6 6: Obeys, 5: Localizes, 4: Withdraws, 3: F...
Endocrinology Intermediate
KING UFC

Diabetic Ketoacidosis Emergency Protocol

KING UFC

Comprehensive bedside management protocol for Diabetic Ketoacidosis (DKA).

K Potassium (K+ Management)
I Insulin (Regular IV Infusion)
N Nasogastric Tube
Infectious Disease Intermediate
PLACESS

Catalase-Positive Pathogens

P L A C E S S

Pathogens capable of decomposing hydrogen peroxide (H2O2), predisposing patients with Chronic Granulomatous Disease (CGD) to recurrent infections.

P Pseudomonas aeruginosa
L Listeria monocytogenes
A Aspergillus fumigatus
Endocrinology Intermediate
CUSHING

Cushing Syndrome Signs: CUSHING

C U S H I N G

Clinical signs of hypercortisolemia resulting from exogenous glucocorticoids, pituitary adenoma, or adrenal tumors.

C Central Obesity / Moon Facies / Buffalo Hu...
U Urinary Free Cortisol Elevated
S Skin Changes (Violaceous Purple Striae)
Psychiatry Beginner
CAGE

Alcohol Use Disorder Screening

C A G E

A 4-question screening tool with high sensitivity for detecting problematic alcohol use or dependence in outpatient settings.

C Cut down
A Annoyed
G Guilty
Pharmacology Intermediate
CRAP GPS

Cytochrome P450 Enzyme Inducers

CRAP GPS

Classic mnemonic for agents that induce hepatic microsomal enzymes, accelerating metabolism of co-administered drugs.

C Carbamazepine
R Rifampin (Rifampicin)
A Alcohol (Chronic Use)
Cardiology Intermediate
JONES CRITERIA

Acute Rheumatic Fever: Jones Criteria

JONES CRITERIA

Major criteria for diagnosing Acute Rheumatic Fever following Group A Streptococcus (GAS) pharyngitis.

J Joints (Migratory Polyarthritis)
O O (Heart / Carditis)
N Nodules (Subcutaneous)
Pulmonology Intermediate
CLUBBING

Clubbing Causes: CLUBBING

C L U B B I N G

High-yield differential diagnosis for digital clubbing (loss of Lovibond angle > 165 degrees).

C Cyanotic Congenital Heart Disease / Cystic...
L Lung Cancer (Bronchogenic Carcinoma)
U Ulcerative Colitis & Crohn's Disease
Pharmacology Intermediate
LEAD LINES

Lead Poisoning Manifestations: LEAD

LEAD LINES

Clinical signs of environmental lead toxicity in pediatric and occupational populations.

L Lead Lines on Gingiva & Metaphyses
E Encephalopathy & Erythrocyte Basophilic St...
A Anemia (Microcytic Sideroblastic) & Abdomi...
Emergency Medicine Intermediate
PARKLAND & RULE OF 9s

Burns Fluid Resuscitation: Parkland Formula & Rule of 9s

PARKLAND & RULE OF 9s

Standardized estimation of total body surface area (TBSA) burned and initial 24-hour crystalloid fluid resuscitation formula.

Head & Neck 9% TBSA (4.5% anterior, 4.5% posterior)
Upper Limbs 9% each (4.5% anterior, 4.5% posterior per...
Trunk 36% TBSA (18% anterior chest/abdomen, 18%...
Gastroenterology Beginner
CURLING vs CUSHING

Stress Gastric Ulcers: Curling vs Cushing

CURLING vs CUSHING

Classic board differentiation between the two physiological stress-induced acute peptic ulcers.

Curling Burn Ulcers
Cushing CNS / ICP Ulcers
Infectious Disease Advanced
SPACE

AmpC Beta-Lactamase Organisms: SPACE

S P A C E

Gram-negative bacterial pathogens possessing inducible chromosomal AmpC beta-lactamases that develop resistance to cephalosporins during therapy.

S Serratia marcescens
P Pseudomonas aeruginosa / Proteus (indole-p...
A Acinetobacter baumannii
Hematology Intermediate
ART OF HUS

Hemolytic Uremic Syndrome Triad

ART OF HUS

The pathognomonic clinical triad of Shiga toxin-mediated thrombotic microangiopathy in pediatric patients.

A Anemia (Microangiopathic Hemolytic Anemia)
R Renal Failure (Acute Oliguria / Anuria)
T Thrombocytopenia
Cardiology Intermediate
BECK'S TRIAD

Cardiac Tamponade: Beck's Triad

BECK'S TRIAD

The pathognomonic physical examination triad indicating acute pericardial fluid accumulation compromising cardiac hemodynamics.

H Hypotension
D Distended Jugular Veins (JVD)
M Muffled Heart Sounds
Cardiology Beginner
SAD

Aortic Stenosis Cardinal Symptoms: SAD

S A D

The classic triad signaling severe hemodynamically significant calcific aortic stenosis and dramatic drop in survival.

S Syncope (Exertional)
A Angina
D Dyspnea / Heart Failure
Neurology Beginner
SOME SAY MARRY MONEY BUT MY BROTHER SAYS BIG BRAINS MATTER MORE

Cranial Nerves Sensory vs Motor: Rhyme

SOME SAY MARRY MONEY BUT MY BROTHER SAYS BIG BRAINS +

The world-famous mnemonic for remembering the functional modality (Sensory, Motor, or Both) of all 12 cranial nerves in order.

CN I (Olfactory Some (Sensory)
CN II (Optic Say (Sensory)
CN III (Oculomotor Marry (Motor)
Endocrinology Intermediate
5 P's OF PHEO

Pheochromocytoma Clinical Features

5 P's OF PHEO

Classic paroxysmal presentation of catecholamine-secreting chromaffin cell tumors of the adrenal medulla.

P Pressure (Severe Hypertension)
P Pain (Pounding Headache)
P Perspiration (Profuse Diaphoresis)
Emergency Medicine Beginner
AMPLE

Trauma Rapid History: AMPLE

A M P L E

The standardized secondary survey history framework in Advanced Trauma Life Support (ATLS).

A Allergies
M Medications (Current)
P Past Medical / Surgical History & Pregnanc...
Emergency Medicine Beginner
OPQRST

Pain Assessment Framework: OPQRST

O P Q R S T

Universal structured method for taking a comprehensive history of presenting pain in clinical practice.

O Onset
P Provocation / Palliation
Q Quality
Neurology Advanced
SPINAL CORD CHEAT SHEET

Spinal Cord Syndromes: Brown-Séquard vs Anterior Cord

SPINAL CORD CHEAT SHEET

Localization cheat sheet for classic incomplete spinal cord injury syndromes.

Brown-Séquard Hemicord Lesion
Anterior Cord Anterior Spinal Artery Infarction
Central Cord Syringomyelia / Hyperextension Trauma
Psychiatry Intermediate
5 A's OF SCHIZOPHRENIA

Schizophrenia Negative Symptoms: 5 A's

5 A's OF SCHIZOPHRENIA

Core negative symptoms of schizophrenia that are often refractory to traditional first-generation antipsychotics.

A Avolition
A Affect Flattening
A Alogia
Cardiology Intermediate
STANFORD A vs B

Aortic Dissection Stanford Classification

STANFORD A vs B

Surgical triage classification determining immediate emergency open operative intervention versus medical management.

Type A Anterior / Ascending Aorta (Surgical Emerg...
Type B Below / Behind Subclavian (Medical Managem...
Pharmacology Beginner
NOT

Aminoglycoside Major Toxicities

N O T

The three classical adverse effect categories of aminoglycoside antibiotics (Gentamicin, Tobramycin, Amikacin).

N Nephrotoxicity
O Ototoxicity
T Teratogen (CN VIII Deafness)
Neurology Intermediate
DANISH

Cerebellar Lesion Localization: DANISH

D A N I S H

Classic neurological physical examination signs indicating ipsilateral cerebellar hemisphere or vermis pathology.

D Dysdiadochokinesia / Dysmetria
A Ataxia (Gait & Limb)
N Nystagmus
Psychiatry Intermediate
COAT

Wernicke Encephalopathy Triad

C O A T

Classic reversible acute triad of thiamine (vitamin B1) deficiency, commonly precipitated by chronic alcoholism.

C Confusion / Encephalopathy
O Ophthalmoplegia / Nystagmus
A Ataxia
Endocrinology Intermediate
5 S's OF ADRENAL CRISIS

Primary Hypoadrenalism: Addisonian Crisis

5 S's OF ADRENAL CRISIS

Life-threatening acute glucocorticoid and mineralocorticoid deficiency triggered by stress, infection, or abrupt steroid withdrawal.

S Salt (Severe Hyponatremia)
S Sugar (Hypoglycemia)
S Shock (Refractory Hypotension)
Nephrology Intermediate
HARD-UP

Normal Anion Gap Metabolic Acidosis

H A R D - U P

Causes of hyperchloremic (normal anion gap) metabolic acidosis (AG 8-12 mEq/L) characterized by reciprocal chloride retention.

H Hyperalimentation (Total Parenteral Nutrit...
A Acetazolamide / Addison Disease
R Renal Tubular Acidosis (Types 1, 2, 4)

System Notice

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