Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Gastroenterology

Non-Alcoholic Fatty Liver Disease

A buildup of fat in the liver caused by metabolic issues like obesity and diabetes, which can lead to liver inflammation, scarring, and failure.

Pediatrics & Gastroenterology

Hirschsprung Disease

A birth defect where missing nerve cells in the distal colon cause functional bowel obstruction, preventing newborns from passing meconium.

Gastroenterology

Acute Cholecystitis

Acute inflammation of the gallbladder, mostly due to gallstone obstruction of the cystic duct, causing severe right upper quadrant pain.

Gastroenterology K85.9

Acute Pancreatitis

Acute pancreatitis is a sudden and extremely painful inflammation of the pancreas, most often caused by gallstones or heavy alcohol use, where the organ begins to digest itself.

Oncology & Gastroenterology

Hepatocellular Carcinoma

The primary cancer of the liver, almost always arising in cirrhotic patients, diagnosed via dynamic imaging and treated by resection, ablation, or transplant.

Gastroenterology

Irritable Bowel Syndrome

A common functional GI disorder causing recurrent abdominal pain associated with changes in stool frequency or form, managed with diet, stress reduction, and symptom-directed medications.

Gastroenterology

Chronic Pancreatitis

Permanent inflammatory scarring of the pancreas leading to intractable pain, malabsorption, and diabetes.

Oncology & Gastroenterology

Pancreatic Adenocarcinoma

An aggressive, desmoplastic cancer of the exocrine pancreas with a poor prognosis, typically presenting late with jaundice, weight loss, and abdominal pain.

Gastroenterology & Genetics

Hemochromatosis

A genetic disorder causing toxic iron overload in organs (liver, heart, pancreas) due to HFE gene mutations leading to hepcidin deficiency.

Gastroenterology & Emergency Medicine

Mallory-Weiss Syndrome

A tear in the inner lining of the esophagus/stomach junction caused by severe vomiting, leading to vomiting of blood.

Gastroenterology

Inflammatory Bowel Disease

A chronic autoimmune condition that causes severe inflammation and sores in the digestive tract, leading to diarrhea, pain, and weight loss.

Oncology & Gastroenterology C22.1

Cholangiocarcinoma

An aggressive cancer of the bile ducts often causing profound jaundice, extremely difficult to cure surgically, and heavily linked to chronic biliary inflammation.

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