Evidence-Based Medical Encyclopedia
Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.
Browse by Specialty
Gastroenterology
Diverticulitis
Inflammation or infection of small pouches in the wall of the large intestine, causing severe lower abdominal pain.
Achalasia
Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.
Primary Biliary Cholangitis
An autoimmune liver disease where the immune system slowly attacks the small bile ducts in the liver, leading to bile buildup, severe itching, and fatigue.
Barrett Esophagus
A change in the lining of the lower esophagus from squamous to intestinal-type cells due to chronic acid reflux, carrying a risk of developing esophageal cancer.
Alcoholic Hepatitis
A life-threatening, acute inflammation of the liver caused by heavy alcohol use, presenting with rapid-onset jaundice and liver swelling.
Pernicious Anemia
An autoimmune disease causing lack of intrinsic factor, preventing Vitamin B12 absorption, and resulting in severe anemia and progressive nerve damage.
Liver Cirrhosis
Extensive scarring of the liver caused by long-term damage, leading to liver failure, portal hypertension, and severe systemic complications.
Peptic Ulcer Disease
A disruption of the gastric or duodenal mucosa primarily caused by H. pylori infection or NSAID use, presenting with dyspepsia and epigastric pain.
Autoimmune Hepatitis
A chronic liver disease where the immune system attacks hepatocytes, characterized by elevated transaminases, autoantibodies, and IgG, treated with immunosuppressants.
Hepatic Encephalopathy
A reversible decline in brain function caused by severe liver disease, leading to confusion, altered sleep, and hand tremors as toxins (like ammonia) build up in the blood.
Gastroesophageal Reflux Disease
Chronic backflow of stomach acid into the esophagus causing heartburn, regurgitation, and potential damage to the esophageal lining.
Crohn Disease
Chronic inflammatory bowel disease causing deep ulcers and scarring anywhere from mouth to anus.