Evidence-Based Medical Encyclopedia
Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.
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Nephrology
Acute Pyelonephritis
A severe bacterial infection of the kidneys, usually ascending from the bladder, causing flank pain, high fever, and systemic illness.
Autosomal Dominant Polycystic Kidney Disease
A genetic disease where hundreds of large cysts grow inside the kidneys, destroying their ability to filter blood and causing massively enlarged kidneys, high blood pressure, and kidney failure.
Chronic Kidney Disease
Irreversible, progressive decline in kidney function occurring over months to years.
Granulomatosis with Polyangiitis
A life-threatening systemic vasculitis driven by PR3-ANCA, causing necrotizing granulomas in the upper/lower respiratory tract and rapidly progressive glomerulonephritis.
Anti-GBM Disease
A life-threatening autoimmune disorder where antibodies attack the lungs and kidneys, causing pulmonary hemorrhage (coughing up blood) and rapidly progressive renal failure.
Nephrogenic Diabetes Insipidus
A condition where the kidneys don't respond to the hormone that tells them to hold onto water, leading to excessive urination and extreme thirst.
Diabetic Nephropathy
Kidney damage caused by diabetes, leading to protein leakage in the urine and progressive loss of kidney function.
Acute Kidney Injury
Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.
Focal Segmental Glomerulosclerosis
A progressive kidney disease characterized by focal and segmental scarring of glomeruli, commonly presenting as nephrotic syndrome and leading to renal failure if untreated.
Lupus Nephritis
Kidney inflammation caused by systemic lupus erythematosus, leading to protein in the urine, high blood pressure, and potential kidney failure if not treated aggressively.
Kidney Stones
Hard deposits of minerals and salts that form in the kidneys and cause excruciating pain when they travel down the urinary tract.
IgA Nephropathy
A kidney disease where abnormal IgA proteins build up in the kidney filters, causing blood in the urine and potential long-term kidney failure.