Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

Browse by Specialty

Urology

Nephrology & Urology

Acute Pyelonephritis

A severe bacterial infection of the kidneys, usually ascending from the bladder, causing flank pain, high fever, and systemic illness.

Neurology

Miller Fisher Syndrome

A Guillain-Barré variant characterized by the triad of ataxia, areflexia, and ophthalmoplegia, strongly associated with anti-GQ1b antibodies.

Neurology & Endocrinology

Hashimoto Encephalopathy

A rare, steroid-responsive encephalopathy presenting with altered mental status and seizures, associated with elevated anti-TPO/anti-Tg antibodies but unrelated to actual thyroid function.

Neurology & Sleep Medicine

Restless Legs Syndrome

An overwhelming evening urge to move the legs to relieve uncomfortable sensations, strongly linked to low brain iron and dopaminergic dysfunction, causing severe insomnia.

Pediatrics & Neurology G80.9

Cerebral Palsy

A non-progressive childhood movement and posture disorder caused by early brain injury, leading to spasticity, delayed motor milestones, and lifelong physical disability.

Neurology

Parkinson Disease

A progressive brain disorder that leads to shaking, stiffness, and difficulty with walking, balance, and coordination.

Neurology

Migraine Headaches

A severe, throbbing headache often on one side of the head, associated with nausea and sensitivity to light, caused by sensitive brain nerves and blood vessels.

Urology & Oncology

Testicular Cancer

A highly curable cancer found mostly in young men, presenting as a painless lump in the testicle, requiring surgery and potentially chemotherapy.

Urology & Oncology

Renal Cell Carcinoma

The most common kidney cancer in adults, arising from renal tubules, often asymptomatic until large, and frequently causing paraneoplastic syndromes.

Urology & Oncology C67.9

Bladder Cancer

A common malignancy of the urinary tract, heavily linked to smoking, typically presenting as painless blood in the urine, and treated with surgery and immunotherapy/chemotherapy.

Neurology & Genetics

Neurofibromatosis Type 1

A genetic condition causing tumors to grow on nerves throughout the body, along with characteristic skin spots and bone abnormalities.

Neurology G12.21

Amyotrophic Lateral Sclerosis

A fatal disease involving progressive destruction of both upper and lower motor neurons, causing devastating muscle weakness, paralysis, and death via respiratory failure usually within 3-5 years.

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