Evidence-Based Medical Encyclopedia
Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.
Browse by Specialty
Rheumatology
Fibromyalgia
A chronic disorder causing widespread body pain, severe fatigue, and brain fog, stemming from how the brain processes pain.
Granulomatosis with Polyangiitis
A life-threatening systemic vasculitis driven by PR3-ANCA, causing necrotizing granulomas in the upper/lower respiratory tract and rapidly progressive glomerulonephritis.
Raynaud Phenomenon
Episodic vasospasm of the digits causing color changes (white, blue, red) in response to cold or stress, either benign (primary) or secondary to autoimmune diseases.
Paget Disease of Bone
A focal disorder of chaotic bone remodeling leading to enlarged, weakened, and easily fractured bones, primarily driven by hyperactive osteoclasts.
Systemic Sclerosis
A rare disease that causes the body to produce too much collagen, leading to hardening and tightening of the skin and damage to internal organs.
Polymyalgia Rheumatica
An inflammatory condition seen in older adults causing severe aching and morning stiffness in the shoulders, neck, and hips, responding remarkably well to low-dose steroids.
Dermatomyositis
An autoimmune disease causing progressive muscle weakness and distinct skin rashes, often linked to an underlying cancer in adults.
Osteoporosis
A disease that weakens bones, making them fragile and more likely to break easily from a minor fall or normal daily activities.
Rheumatoid Arthritis
A chronic autoimmune disease causing symmetric joint pain, swelling, and stiffness, which can lead to permanent joint damage if untreated.
Osteoarthritis
A wear-and-tear condition where the cartilage protecting the ends of bones wears down, causing pain, stiffness, and bone-on-bone friction in joints like the knees and hips.
Ankylosing Spondylitis
An inflammatory disease of the spine and sacroiliac joints causing chronic back pain, morning stiffness, and eventual fusion of the vertebrae, primarily affecting young HLA-B27 positive males.
Systemic Lupus Erythematosus
A complex autoimmune disease where the body's immune system attacks its own tissues and organs, often causing a butterfly-shaped facial rash, joint pain, and kidney damage.