Evidence-Based Medical Encyclopedia
Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.
Browse by Specialty
Featured Conditions
Achalasia
Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.
Acromegaly
Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.
Acute Coronary Syndrome
Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.
Acne Vulgaris
Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.
Acute Lymphoblastic Leukemia
A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.
Acute Kidney Injury
Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.
Trending Now
Fibromyalgia
A chronic disorder causing widespread body pain, severe fatigue, and brain fog, stemming from how the brain processes pain.
Achalasia
Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.
Autosomal Dominant Polycystic Kidney Disease
A genetic disease where hundreds of large cysts grow inside the kidneys, destroying their ability to filter blood and causing massively enlarged kidneys, high blood pressure, and kidney failure.
Liver Cirrhosis
Extensive scarring of the liver caused by long-term damage, leading to liver failure, portal hypertension, and severe systemic complications.
Cushing Syndrome
A hormonal disorder caused by prolonged exposure to inappropriately high levels of cortisol.
Chronic Kidney Disease
Irreversible, progressive decline in kidney function occurring over months to years.
Recently Updated
Pulmonary Arterial Hypertension
A progressive disease causing severe narrowing of the lung arteries, leading to high pressure in the lungs and ultimately right-sided heart failure.
Cytomegalovirus Retinitis
A devastating viral eye infection causing retinal destruction and blindness, occurring in severely immunocompromised patients, particularly those with advanced HIV/AIDS.
Metabolic Syndrome
A dangerous combination of belly fat, high blood pressure, high blood sugar, and abnormal cholesterol that dramatically increases the risk of heart attacks and diabetes.
Mitral Valve Prolapse
A condition where the mitral valve leaflets bulge back into the left atrium during the heart's contraction, sometimes causing a leak (regurgitation).
Guillain-Barré Syndrome
An acute autoimmune nerve disorder triggered by a recent infection, causing rapidly worsening, ascending muscle weakness and loss of reflexes.
Polycythemia Vera
A slow-growing blood cancer causing the bone marrow to make too many red blood cells, making the blood dangerously thick and prone to clotting.
Prostate Cancer
An androgen-dependent adenocarcinoma of the prostate gland, often asymptomatic early on but can progress to metastatic bone disease if untreated.
Deep Vein Thrombosis
A blood clot in a deep vein, usually in the leg, that can cause local damage or break off and travel to the lungs.
Peripheral Artery Disease
Atherosclerotic narrowing of lower extremity arteries causing reduced blood flow, presenting as leg pain with walking (claudication) and carrying a high risk for cardiovascular events.
Pancreatic Adenocarcinoma
An aggressive, desmoplastic cancer of the exocrine pancreas with a poor prognosis, typically presenting late with jaundice, weight loss, and abdominal pain.
Hemochromatosis
A genetic disorder causing toxic iron overload in organs (liver, heart, pancreas) due to HFE gene mutations leading to hepcidin deficiency.
Huntington Disease
An inherited, fatal neurodegenerative disease causing chorea, dementia, and psychiatric issues, caused by CAG repeat expansions in the HTT gene.