Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Featured Conditions

Gastroenterology K22.0

Achalasia

Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Cardiology I24.9

Acute Coronary Syndrome

Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology N17.9

Acute Kidney Injury

Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.

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Gastroenterology & Emergency Medicine

Mallory-Weiss Syndrome

A tear in the inner lining of the esophagus/stomach junction caused by severe vomiting, leading to vomiting of blood.

Neurology I63.9

Acute Ischemic Stroke

An acute ischemic stroke is a 'brain attack' where a blood clot blocks blood flow to a part of the brain, causing sudden weakness, speech difficulty, or vision loss.

Rheumatology M06.9

Rheumatoid Arthritis

A chronic autoimmune disease causing symmetric joint pain, swelling, and stiffness, which can lead to permanent joint damage if untreated.

Rheumatology

Osteoarthritis

A wear-and-tear condition where the cartilage protecting the ends of bones wears down, causing pain, stiffness, and bone-on-bone friction in joints like the knees and hips.

Rheumatology M45.9

Ankylosing Spondylitis

An inflammatory disease of the spine and sacroiliac joints causing chronic back pain, morning stiffness, and eventual fusion of the vertebrae, primarily affecting young HLA-B27 positive males.

Nephrology

Lupus Nephritis

Kidney inflammation caused by systemic lupus erythematosus, leading to protein in the urine, high blood pressure, and potential kidney failure if not treated aggressively.

Pulmonology E87.2

Arterial Blood Gas Disorders

Dangerous imbalances in the blood's acidity and oxygen levels caused by severe lung, kidney, or metabolic diseases. Diagnosis requires drawing blood directly from an artery.

Rheumatology M32.9

Systemic Lupus Erythematosus

A complex autoimmune disease where the body's immune system attacks its own tissues and organs, often causing a butterfly-shaped facial rash, joint pain, and kidney damage.

Oncology & Pulmonology

Non-Small Cell Lung Cancer

The most common type of lung cancer, encompassing adenocarcinoma and squamous cell carcinoma, frequently linked to smoking but heavily treated with new targeted and immunotherapies.

Cardiology

Myocarditis

Inflammation of the heart muscle, often triggered by a viral infection, which can weaken the heart and cause irregular heartbeats.

Diabetic Retinopathy

A progressive complication of diabetes resulting in damage to the retinal blood vessels, potentially leading to vision loss.

Gastroenterology

Inflammatory Bowel Disease

A chronic autoimmune condition that causes severe inflammation and sores in the digestive tract, leading to diarrhea, pain, and weight loss.

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