Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Featured Conditions

Gastroenterology K22.0

Achalasia

Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Cardiology I24.9

Acute Coronary Syndrome

Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology N17.9

Acute Kidney Injury

Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.

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Endocrinology

Hyperthyroidism

An overactive thyroid gland causing accelerated metabolism, rapid heart rate, and weight loss.

Oncology

Non-Hodgkin Lymphoma

A diverse group of blood cancers that start in lymphocytes (white blood cells), causing swollen lymph nodes and potentially spreading throughout the body.

Urology

Benign Prostatic Hyperplasia

Age-related non-cancerous prostate enlargement causing urinary obstruction and LUTS.

Otolaryngology & Pediatrics

Acute Otitis Media

A common bacterial or viral infection of the middle ear, mostly seen in young children, causing ear pain, fever, and a bulging eardrum.

Hematology

Sickle Cell Disease

An inherited genetic blood disorder where abnormal hemoglobin causes red blood cells to become sickle-shaped, leading to severe pain episodes, chronic anemia, and organ damage.

Neurology

Bell Palsy

Idiopathic acute unilateral lower motor neuron facial nerve paralysis.

Gastroenterology

Celiac Disease

Autoimmune damage to the small intestine triggered by eating gluten, leading to malabsorption.

Infectious Diseases

Syphilis

A multi-stage sexually transmitted bacterial infection causing painless sores, followed by systemic rashes, and potentially ending in severe brain and heart damage if left untreated.

Neurology

Multiple Sclerosis

An autoimmune disease of the central nervous system where the body's immune system attacks myelin, causing varied neurological symptoms.

Pulmonology

Chronic Obstructive Pulmonary Disease

Chronic inflammatory lung disease that causes irreversible obstructed airflow, primarily from smoking.

Nephrology

IgA Nephropathy

A kidney disease where abnormal IgA proteins build up in the kidney filters, causing blood in the urine and potential long-term kidney failure.

Neurology & Psychiatry G31.83

Dementia with Lewy Bodies

A progressive dementia causing fluctuating confusion, detailed visual hallucinations, and Parkinson-like stiffness, with severe reactions to typical antipsychotic drugs.

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