Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Featured Conditions

Gastroenterology K22.0

Achalasia

Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Cardiology I24.9

Acute Coronary Syndrome

Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology N17.9

Acute Kidney Injury

Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.

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Dermatology

Hidradenitis Suppurativa

A chronic, painful skin condition causing recurring boils and tunnels under the skin, usually in the armpits and groin.

Oncology

Melanoma

A deadly form of skin cancer that starts in pigment cells, often looking like an irregular, changing mole, and requires surgical removal before it spreads.

Rheumatology M34.9

Systemic Sclerosis

A rare disease that causes the body to produce too much collagen, leading to hardening and tightening of the skin and damage to internal organs.

Dermatology L20.9

Atopic Dermatitis

A chronic skin condition causing severely dry, red, itchy patches. Known as 'the itch that rashes,' it mostly affects children but can persist into adulthood.

Esophageal Cancer

A deadly cancer of the food pipe often discovered at an advanced stage, typically causing progressive difficulty swallowing solid foods.

Endocrinology E11.9

Type 2 Diabetes Mellitus

A common condition where the body becomes resistant to its own insulin, causing blood sugar levels to rise dangerously high over time.

Cardiology I48.91

Atrial Fibrillation

A chaotic, irregular heartbeat that causes poor blood flow and massively increases the risk of forming blood clots in the heart, leading to stroke.

Pulmonology

Obstructive Sleep Apnea

A condition where the airway repeatedly collapses during sleep, stopping breathing and causing severe snoring, poor sleep, and daytime sleepiness.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology E11.21

Diabetic Nephropathy

Kidney damage caused by diabetes, leading to protein leakage in the urine and progressive loss of kidney function.

Urology & Oncology

Renal Cell Carcinoma

The most common kidney cancer in adults, arising from renal tubules, often asymptomatic until large, and frequently causing paraneoplastic syndromes.

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