Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Featured Conditions

Gastroenterology K22.0

Achalasia

Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Cardiology I24.9

Acute Coronary Syndrome

Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology N17.9

Acute Kidney Injury

Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.

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Pulmonology

Idiopathic Pulmonary Fibrosis

A fatal disease where the lungs become progressively scarred and stiff for unknown reasons, making breathing extremely difficult.

Endocrinology E05.00

Graves Disease

An autoimmune condition where the immune system overstimulates the thyroid gland, causing it to produce too much thyroid hormone and leading to a rapid heart rate, weight loss, and sometimes bulging eyes.

Endocrinology & Rheumatology

Paget Disease of Bone

A focal disorder of chaotic bone remodeling leading to enlarged, weakened, and easily fractured bones, primarily driven by hyperactive osteoclasts.

Neurology

Parkinson Disease

A progressive brain disorder that leads to shaking, stiffness, and difficulty with walking, balance, and coordination.

Neurology

Migraine Headaches

A severe, throbbing headache often on one side of the head, associated with nausea and sensitivity to light, caused by sensitive brain nerves and blood vessels.

Endocrinology E27.1

Addison Disease

Addison disease occurs when the adrenal glands are damaged and cannot produce enough cortisol and aldosterone, leading to severe fatigue, low blood pressure, weight loss, and skin darkening.

Endocrinology E21.0

Primary Hyperparathyroidism

A condition where a benign tumor on a parathyroid gland produces too much parathyroid hormone, pulling calcium out of bones and into the blood.

Infectious Diseases A97.9

Dengue Fever

A tropical viral illness transmitted by mosquitoes, characterized by high fever, severe body aches, and in severe cases, dangerous internal bleeding and shock.

Hematology

Iron Deficiency Anemia

A lack of iron leading to a reduced number of healthy red blood cells, causing fatigue and weakness.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Obstetrics & Gynecology

Preeclampsia & Eclampsia

A dangerous pregnancy complication marked by high blood pressure and organ damage, which can progress to life-threatening seizures (eclampsia).

Pulmonology J45.909

Asthma

A chronic lung disease causing episodes of airway narrowing and mucus production, leading to wheezing and shortness of breath. Controlled with daily inhaled steroids.

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