Evidence-Based Medical Encyclopedia
Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.
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Featured Conditions
Achalasia
Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.
Acromegaly
Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.
Acute Coronary Syndrome
Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.
Acne Vulgaris
Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.
Acute Lymphoblastic Leukemia
A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.
Acute Kidney Injury
Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.
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Fibromyalgia
A chronic disorder causing widespread body pain, severe fatigue, and brain fog, stemming from how the brain processes pain.
Achalasia
Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.
Autosomal Dominant Polycystic Kidney Disease
A genetic disease where hundreds of large cysts grow inside the kidneys, destroying their ability to filter blood and causing massively enlarged kidneys, high blood pressure, and kidney failure.
Liver Cirrhosis
Extensive scarring of the liver caused by long-term damage, leading to liver failure, portal hypertension, and severe systemic complications.
Cushing Syndrome
A hormonal disorder caused by prolonged exposure to inappropriately high levels of cortisol.
Chronic Kidney Disease
Irreversible, progressive decline in kidney function occurring over months to years.
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Kawasaki Disease
An acute childhood vasculitis causing prolonged fever, rash, and mucous membrane inflammation, which can lead to life-threatening coronary artery aneurysms if untreated.
Aplastic Anemia
A condition where the body's immune system destroys its own bone marrow, stopping the production of all blood cells and leading to severe fatigue, bleeding, and infections.
Hypercalcemia of Malignancy
A life-threatening metabolic complication of advanced cancer causing very high calcium levels due to tumor-secreted hormones (PTHrP) or bone metastases.
Chronic Myeloid Leukemia
A clonal bone marrow disease driven by the Philadelphia chromosome (BCR-ABL1), leading to massive overproduction of white blood cells and curable with targeted tyrosine kinase inhibitors.
Crohn Disease
Chronic inflammatory bowel disease causing deep ulcers and scarring anywhere from mouth to anus.
Mumps
A highly contagious viral infection that causes painful swelling of the salivary glands in the cheeks and jaw.
Non-Alcoholic Fatty Liver Disease
A buildup of fat in the liver caused by metabolic issues like obesity and diabetes, which can lead to liver inflammation, scarring, and failure.
Acute Coronary Syndrome
Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.
Kaposi Sarcoma
A cancer caused by a virus (HHV-8) that produces purple skin lesions and affects internal organs, mostly in people with weakened immune systems like advanced HIV.
Heart Failure with Preserved Ejection Fraction
A type of heart failure where the heart pumps normally but is too stiff to relax and fill properly with blood, causing fluid backup into the lungs and body.
Testicular Cancer
A highly curable cancer found mostly in young men, presenting as a painless lump in the testicle, requiring surgery and potentially chemotherapy.
Heart Failure with Reduced Ejection Fraction
A condition where the heart muscle is weak and dilated, failing to pump enough blood to the body, characterized by an ejection fraction of 40% or lower.