Disease Knowledge Center

Evidence-Based Medical Encyclopedia

Explore thousands of diseases with authoritative clinical information from WHO, CDC, NIH, and international medical guidelines. Every condition features an interactive journey from diagnosis to treatment.

200 Diseases
60 Specialties
276 Sources

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Featured Conditions

Gastroenterology K22.0

Achalasia

Achalasia is an esophageal motility disorder caused by nerve degeneration, resulting in failure of the lower esophageal sphincter to relax and progressive difficulty swallowing.

Endocrinology E22.0

Acromegaly

Acromegaly is a hormonal disorder caused by a pituitary tumor producing too much growth hormone, leading to enlarged hands, feet, and facial features.

Cardiology I24.9

Acute Coronary Syndrome

Acute Coronary Syndrome is a heart attack or severe angina caused by a sudden blockage in a coronary artery, cutting off blood and oxygen to the heart muscle.

Dermatology L70.0

Acne Vulgaris

Acne vulgaris is a common inflammatory skin condition caused by blocked hair follicles and oil glands, leading to pimples, blackheads, and cysts.

Hematology & Oncology

Acute Lymphoblastic Leukemia

A rapid-onset blood cancer where immature white blood cells (lymphoblasts) multiply uncontrollably in the bone marrow, crowding out healthy cells.

Nephrology N17.9

Acute Kidney Injury

Acute Kidney Injury is a sudden loss of kidney function, often due to decreased blood flow, toxins, or blockages, leading to a dangerous buildup of waste and fluids.

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Psychiatry

Post-Traumatic Stress Disorder

A debilitating mental health condition triggered by experiencing or witnessing a terrifying event, causing flashbacks, nightmares, and severe anxiety.

Pulmonology D86.9

Sarcoidosis

An inflammatory disease where tiny collections of immune cells (granulomas) grow in the lungs, lymph nodes, and other organs, causing coughing and shortness of breath.

Dermatology

Pemphigus Vulgaris

A severe autoimmune condition causing painful, easily broken blisters and sores on the skin and inside the mouth.

Oncology & Gynecology

Ovarian Cancer

A highly deadly cancer of the female reproductive glands, usually diagnosed late because its early symptoms are vague like bloating and pelvic pain.

Gastroenterology & Hepatology K75.4

Autoimmune Hepatitis

A chronic liver disease where the immune system attacks hepatocytes, characterized by elevated transaminases, autoantibodies, and IgG, treated with immunosuppressants.

Neurology & Sleep Medicine

Restless Legs Syndrome

An overwhelming evening urge to move the legs to relieve uncomfortable sensations, strongly linked to low brain iron and dopaminergic dysfunction, causing severe insomnia.

Rheumatology & Vascular Medicine

Raynaud Phenomenon

Episodic vasospasm of the digits causing color changes (white, blue, red) in response to cold or stress, either benign (primary) or secondary to autoimmune diseases.

Pediatrics & Neurology G80.9

Cerebral Palsy

A non-progressive childhood movement and posture disorder caused by early brain injury, leading to spasticity, delayed motor milestones, and lifelong physical disability.

Hepatology & Radiology

Hepatic Hemangioma

The most common benign liver tumor, consisting of blood-filled vascular spaces, usually discovered incidentally and requiring no treatment.

Otolaryngology

Sialadenitis & Parotitis

Painful swelling of the salivary glands (usually parotid or submandibular) caused by bacterial infection, viral mumps, stones, or autoimmune disease.

Oncology C50.919

Breast Cancer

A malignancy of the breast ducts or lobules, highly treatable when caught early, whose management depends on the presence of estrogen, progesterone, and HER2 receptors.

Infectious Diseases & Pediatrics

Infectious Mononucleosis

A viral infection famous for causing severe fatigue, sore throat, and swollen lymph nodes, often called the 'kissing disease'.

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